It is our pleasure to welcome Moira Rachman from the University of Barcelona for three months. Moira will work on the fragment-based design of novel JAK inhibitors.
We are happy to welcome our newest group member, Helga Bereczki, who will work on synthetic and analytical chemistry.
We are happy to welcome back Krzysztof Rataj from the Polish Academy of Sciences (Warsaw, Poland), who will collaborate with us in GPCR-directed computational drug discovery.
National Competitiveness and Excellence Program (NVKP) Grant
Our group has received a National Competitiveness and Excellence Program (NVKP) Grant from the National Research, Development and Innovation Office to support our proposal on the research of pediatric malignancies, which are the leading causes of death for children below 14 years (NVKP_16-1-2016-0037). Although current haemato-oncological treatments can facilitate full recovery, solid tumours are lethal within 10 years for around half of the affected patients. Through a joint research effort with the 2nd Department of Pediatrics of the Semmelweis University and Meditop Pharmaceutical Ltd., we are planning to utilize state-of-the-art DNA sequencing techniques to identify biomarkers that correlate with the occurrence of these malignancies, propose protein targets for their treatment, and ultimately, identify and synthesize drug candidates that display promising effect on the given target. During this project, we will gain novel insight into the molecular and epidemiological background of the development of solid tumors, create a DNA sequencing test for prevention and targeted diagnostics, and hopefully improve the clinical prospects of pediatric patients with solid tumors.
György M Keserű, head of the research group, has been named as a Fellow of the Royal Society of Chemistry (RSC), a professional society based in the United Kingdom with over 50,000 members worldwide. Founded in 1841, RSC is the largest organization in Europe for advancing the chemical sciences. RSC partners with industry and academia, advises governments on policy, and promotes the talent, collaboration, innovation, information and ideas that lead to great advances in science. The designation Fellow of the Royal Society of Chemistry (FRSC) is given to elected Fellows who have made significant contributions to the chemical sciences. The names of newly elected Fellows are published each year in The Times (London). For more information on the Royal Society of Chemistry, please visit the official website here.
We are happy to welcome back Krzysztof Rataj from the Polish Academy of Sciences (Warsaw, Poland), who will collaborate with us in GPCR-directed drug discovery.
New PhD students join our group
With the support of the FRAGments training NETwork (H2020-MSCA-ITN-2015 No. 675899 FRAGNET), two PhD students have joined our research group for a 3-year period, including a full PhD programme at the Budapest University of Technology and Economics. We are happy to welcome Aaron Keeley (from University College Dublin, Ireland) and Andrea Scarpino (from University of Pisa, Italy), who will conduct synthetic and computational chemical research on fragment-based approaches in the development of covalent binders against relevant drug targets.
We are happy to welcome Janez Ilaš from the University of Ljubljana (Slovenia), who joins our research group for three months to collaborate with us in the biophysical characterization of enzyme inhibitors.
We are happy to welcome three new students: Zsófia Laskai, Márton Nagyházi and Valentina Varga as the newest members as the newest members of the Medicinal Chemistry Research Group.
We are happy to welcome Krzysztof Rataj from the Polish Academy of Sciences (Warsaw, Poland), who joins our research group for two weeks to collaborate with us in GPCR-directed drug discovery.
We are happy to welcome a PhD student, László Petri and five university students, Levente Kollár, Blanka Rinyu, Dénes Sóvári, Gabriella Suhó and Csaba Szabó as the newest members of the Medicinal Chemistry Research Group.
Our paper titled Discovery of Subtype Selective Janus Kinase (JAK) Inhibitors by Structure-Based Virtual Screening is selected for the cover image of the current issue of the Journal of Chemical Information and Modeling.
József Balog has successfully defended his PhD thesis (Synthesis of novel isoquinoline derivatives) at the Budapest University of Technology and Economics. Congratulations, Józsi!
We are happy to welcome Attila Egyed, Dóra Judit Kiss and Zoltán Orgován as the newest members of our research group.
The European Union has granted 3.9 M euro to our consortium from academia and SMEs from Hungary, The Netherlands, Spain, Sweden, Switzerland, and UK. The funding enables the consortium to establish the Marie Curie Innovative Training Network (ITN) FRAGNET of 15 PhD students and explore new research methods and applications in the emerging field of Fragment-Based Lead Discovery.
Hungarian Scientific Research Fund Grant
We are proud to be the recipients of a Hungarian Scientific Research Fund (OTKA) grant for our research on Janus kinase inhibitors. Read more on our ongoing research projects here.